{"id":208,"date":"2023-09-04T10:36:22","date_gmt":"2023-09-04T10:36:22","guid":{"rendered":"https:\/\/phlebodia.uz\/?page_id=208"},"modified":"2023-11-06T07:41:14","modified_gmt":"2023-11-06T07:41:14","slug":"instruction","status":"publish","type":"page","link":"https:\/\/phlebodia.uz\/uz\/instruction\/","title":{"rendered":"Qo'llanma"},"content":{"rendered":"\t\t
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\u0424\u043b\u0435\u0431\u043e\u0434\u0438\u0430 600<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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TIBBIYOTDA QO\u2019LLANILISHIGA DOIR YO\u2019RIQNOMA
\nFLEBODIA 600\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Preparatning savdo nomi: <\/strong>FLEBODIA 600<\/p>

Ta\u2019sir etuvchi modda (XPN): <\/strong>diosmin (diosmine)<\/p>

Dori shakli: <\/strong>qobiq bilan qoplangan tabletkalar.<\/p>

Tarkibi:<\/strong><\/p>

Bir tabletka:<\/strong><\/p>

faol modda: <\/em><\/p>

diosmin quruq moddaga qayta hisoblaganda……………600 mg<\/p>

yordamchi moddalar:<\/em><\/p>

talk………………………………………………………………………10,24 mg<\/p>

kolloid kremniy dioksidi……………………………………..3,5 mg<\/p>

stearin kislotasi…………………………………………………..50,05 mg<\/p>

mikrokristallik sellyuloza………………………………….910 mg gacha<\/p>

Plyonka qobiq tarkibi: <\/em><\/p>

Sepifilm\u00ae 002 (gipromelloza (E 464) \u2013 9,832 mg, mikrokristallik sellyuloza \u2013 7,866 mg, makrogol 8 stearat 1 turi \u2013 1,967 mg).<\/p>

pushti Sepispers\u00ae AR 5523 (propilenglikol izlari, gipromelloza (E 464) \u2013 0,458 mg, titan dioksidi (E171) \u2013 4,026 mg, puns bo\u2019yovchi [Ponso 4R] (E124) \u2013 0,401 mg, temir (II, III) oksidi (E172) — 0,130 mg,\u00a0 temir (III) oksidi (E172) \u2013 0,020 mg)<\/p>

Opaglos\u00ae 6000 (karnaub mumi (E 903) — 0,075 mg, asalari mumi (E 901) \u2013 0,075 mg, shellak (E 904) \u2013 0,150 mg,\u00a0 etanol\u00a0 95\u00b0 — izlari)<\/p>

Ta\u2019rifi: <\/strong>dumaloq, ikkiyoqlama qabariq, pushti rangli qobiq bilan qoplangan tabletkalar.<\/p>

Farmakoterapevtik guruhi: <\/strong>Angioprotektor vosita.<\/p>

ATX \u00a0kodi:<\/strong> \u00a0\u042105\u0421\u041003<\/p>

\u00a0<\/strong><\/p>

Farmakologik xususiyatlari<\/strong><\/p>

Farmakodinamikasi<\/em><\/p>

Preparat flebotonuslovchi ta\u2019sirga ega: venalarning cho\u2019ziluvchanligini kamaytiradi, venalarning tonusini oshiradi (dozaga bog\u2019liq samara), venoz dimlanishni kamaytiradi, limfatik drenajni yaxshilaydi: limatik kapillyarlarning tonusini va qisqarishlari tez-tezligini oshiradi, ularning funksional zichligini oshiradi, limfatik bosimni pasaytiradi; mikrotsirkulyatsiyani yaxshilaydi: kapillyarlarning chidamliligini oshiradi (dozaga bog\u2019liq samara), ularning o\u2019tkazuvchanligini kamaytiradi; leykotsitlarning vena devorlariga yopishqoqligini (adgezivligi) va ularning vena atrofidagi to\u2019qimalariga migratsiyasini kamaytiradi; teri to\u2019qimasiga kislorodning diffuziyasini va perfuziyani yaxshilaydi, yallig\u2019lanishga qarshi ta\u2019sirga ega. Adrenalinning, noradrenalinning tomirlarni toraytiruvchi ta\u2019sirini kuchaytiradi, erkin radikallarning ajralib chiqishini, prostaglandinlar va tromboksanning sintezini bloklaydi.<\/p>

Farmakokinetikasi<\/em><\/p>

Me\u2019da-ichak yo\u2019llaridan tez so\u2019riladi, qabul qilinganidan so\u2019ng 2 soatdan keyin plazmada aniqlanadi. Qon plazmasida maksimal konsentratsiyaga qabul qilinganidan so\u2019ng 5 soatdan keyin erishiladi. Bir tekis taqsimlanadi va kavak venalarning va oyoq-qo\u2019llarning teri osti venalarining hamma qavatlarida, kam darajada \u2013 buyraklarda, jigar va o\u2019pkalarda va boshqa to\u2019qimalarda to\u2019planadi. Diosmin va\/yoki uning metabolitlarining vena tomirlarida tanlab to\u2019planishi qabul qilingandan so\u2019ng 9 soatdan keyin maksimal darajaga erishadi va 96 soat davomida saqlanadi. 79% — siydik, 11% — ahlat, 2,4% — o\u2019t-safro bilan chiqariladi.<\/p>

\u00a0<\/strong><\/p>

Q<\/strong>o\u2019llanilishi<\/strong><\/p>

— pastki tayanch harakat a\u2019zolari limfavenoz yetishmovchiligi belgilarini bartaraf etish uchun: oyoqlarda og’irlik yoki charchoq hissi, og’riq, bezovta oyoq sindromi;<\/p>

— mikrosirkulyatsiya buzilishida yordamchi terapiya;<\/p>

— o’tkir gemoroyning simptomatik terapiyasi.<\/p>

\u00a0<\/strong><\/p>

Qo\u2019llash usuli va dozalari<\/strong><\/p>

Har doim ushbu yo\u2018riqnomada keltirilgan yoki shifokoringiz yoki farmasevtingizdan olingan ma\u2019lumotga qat\u2019iy rioya qilgan holda preparatni qabul qilishingiz kerak.<\/p>

Agar shubhangiz bo’lsa, shifokor yoki farmatsevt bilan maslahatlashing.<\/p>

Ichish uchun.<\/p>

Dozalash<\/p>